Science & Industry is a notable Multiplayer GoldSRC mod that has been active since the very early days of Half-Life modding. During a typical S&I game, two teams (MCL and AFD, Blue and Green respectively) battle to control a map's quota of NPC scientists in order to accumulate money and accelerate research into heavier weaponry, statistical boosts and other gadgets.
The mod has a small but loyal following but has had difficulty in finding new players due to an expansive, democratically selected tech-tree that makes or breaks a team's combat capability. It offers a deeply tactical approach to basic Half-Life death-matching and many veteran players have HLDM backgrounds.
A Source-powered sequel is in production, though it has seen slow development thus far.