Left 4 Dead is set in contemporary America gone wrong. There are both rural and urban areas in the four campaigns. Each campaign has around 5 maps. They take place in the following:

• No Mercy - An urban campaign through city streets and ending on a hospital roof
     
• Blood Harvest - A forested campaign ending in a farmhouse in the middle of a cornfield
     
• Dead Air - Transpires almost entirely on rooftops and ends at an airport
     
• Death Toll - Set in murky woods and underground